A day trip from Milan to Lake Como is a refreshing break from city life. For centuries this Y-shaped lake has been a posh retreat for the upper classes, and today that luxurious lifestyle remains. Referred to by some as the most beautiful lake in the world, touring the villages of Bellagio, Varenna, and Tremezzo is a must for any traveler. More lakeside attractions include the grand Villa Carlotta, the 12th-century Castello di Vezio, and the monumental Como Cathedral.

Around 80 kilometers (50 miles) north of Milan, trains reach Lake Como in anywhere from an hour and 40 minutes to two and a half hours. Driving or taking the bus can cut the travel time by almost an hour, clocking in at an average of 90 minutes.

The port city of Genoa is a center of culture that’s perfect for a day away from the tumult of Milan. Revel in the heartbeat of the city at Piazza dei Ferrari, take in the splendor of the Royal Palace, and admire the palaces lining the Via Garibaldi. Set aside some time to taste the local sausage, known worldwide as Genoa salami.

Head the 150 kilometers (93 miles) south of Milan by car or bus and you will reach Genoa in around two hours. By train, the journey is a bit quicker at around 90 minutes.

Embarking on a day out to Bergamo is a wonderful way to explore the oldest town in the hilly region. Some of the town’s can’t-miss attractions include the Piazza Vecchia and the Basilica di Santa Maria Maggiore, a church built in 1137. Climb the Campanone tower for unbeatable views of the city and make sure to visit the Donizetti Museum dedicated to the renowned local composer.

It will take a little less than an hour to travel the 51 kilometers (31 miles) to Bergamo from Milan by car. By rail, the trip depends on which train you decide to take, but travel ranges between 45 minutes and two hours.